Pulmonary alveolar proteinosis with secondary Aspergillus infection: A case report

Authors

  • Fanny Fachrucha Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia https://orcid.org/0000-0001-9450-2180
  • Sita Andarini Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia
  • Mia Elhidsi Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia https://orcid.org/0000-0002-5005-044X
  • Rizky Yudha Irawan Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia https://orcid.org/0000-0003-4187-919X
  • Romi Beginta Department of Anatomic Pathology, Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia
  • Dianiati Kusumo Sutoyo Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia

DOI:

https://doi.org/10.17532/jhsci.2021.1366

Keywords:

Fungal infection, milky appearance bronchoalveolar lavage fluid, pulmonary alveolar proteinosis, whole lung lavage

Abstract

Pulmonary alveolar proteinosis (PAP) is a rare disease with mostly due to autoimmune toward granulocyte-macrophage colony-stimulating factor. In some conditions, PAP followed with secondary infection. A 34-year-old woman came with progressive shortness of breath, chronic dry cough, and mild fever. The chest High-Resolution Computed Tomography showed ground-glass opacity with septal reticulation or known as the crazy-paving pattern, and a cavity on the upper lobe of the left lung. The patient underwent bronchoscopy for diagnostic and therapeutic measures and found milky appearance bronchoalveolar lavage fluid (BALF). The serum galactomannan came out positive. Fungal infection detected from the BALF culture, Aspergillus fumigatus, hence fulfilling the diagnosis of PAP with probable invasive pulmonary aspergillosis. The patient showed clinical improvement after undergoing whole lung lavage and given anti-fungal medications.


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Published

30.12.2021

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Section

Case reports

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How to Cite

1.
Pulmonary alveolar proteinosis with secondary Aspergillus infection: A case report. JHSCI [Internet]. 2021 Dec. 30 [cited 2024 Oct. 14];11(3):191-5. Available from: https://www.jhsci.ba/ojs/index.php/jhsci/article/view/1366