Leber’s hereditary optic neuropathy - case report

Authors

  • Mirjana A. Janicijevic Petrovic Clinic of Ophthalmology Clinical Centre Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, Serbia.
  • Tatjana Sarenac Vulovic Clinic of Ophthalmology Clinical Centre Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, Serbia.
  • Nenad Petrovic Clinic of Ophthalmology Clinical Centre Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, Serbia.
  • Suncica Sreckovic Clinic of Ophthalmology Clinical Centre Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, Serbia.
  • Svetlana Paunovic Clinic of Ophthalmology Clinical Centre Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, Serbia.
  • Katarina Janicijevic Medical Faculty of University in Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia
  • Dejan Vulovic Medical Faculty of University in Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia
  • Dragan Vujic State University of Novi Pazar, Vuka Karadžića bb, 36300 Novi Pazar, Serbia.

DOI:

https://doi.org/10.17532/jhsci.2012.54

Keywords:

optic neuropathy, Leber, visual acuity

Abstract

Leber’s hereditary optic neuropathy is a neuro-ophthalmological entity characterized by acute or subacute bilateral, not simultaneous visual loss with centro cekal scotoma and occasional further visual improvement. This rare ophthalmological disease can be accompanied with dyschromatopsia. It is associated with a matrilineal inheritance pattern. Its diagnosis used to be solely clini¬cal, aided by imaging and neuro-physiological studies, until the advent of descriptions of mitochondrial biochemical abnormalities and genetic testing. We describe a case of 24 year old male with progressive painless deterioration of visual acuity and positive family history.

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Published

15.09.2012

Issue

Section

Research articles

How to Cite

1.
Leber’s hereditary optic neuropathy - case report. JHSCI [Internet]. 2012 Sep. 15 [cited 2024 Jul. 18];2(2):148-52. Available from: https://www.jhsci.ba/ojs/index.php/jhsci/article/view/73