Common variable immunodeficiency – case report

Authors

  • Emina Vukas Pediatric clinic, Clinical centre University in Sarajevo, Patriotske lige 81, 71000 Sarajevo, Bosnia and Herzegovina
  • Aida Dizdarević Pediatric clinic, Clinical centre University in Sarajevo, Patriotske lige 81, 71000 Sarajevo, Bosnia and Herzegovina
  • Senka Mesihović - Dinarević Pediatric clinic, Clinical centre University in Sarajevo, Patriotske lige 81, 71000 Sarajevo, Bosnia and Herzegovina
  • Adisa Čengić Pediatric clinic, Clinical centre University in Sarajevo, Patriotske lige 81, 71000 Sarajevo, Bosnia and Herzegovina

DOI:

https://doi.org/10.17532/jhsci.2013.83

Keywords:

Common variable immunodeficiency, hypogammaglobulinemia, immune system

Abstract

Common variable immunodeficiency (CVID) or acquired hypogammaglobulinemia is the type of primary immunodeficiency. Deregulation of the immune system, leading to hypogammaglobulinemia, defective activation and proliferation of T cells and dendritic cells, and malfunction of the cytokines are observed in CVID. The clinical picture of CVID varies, any organ or system can be affected, therefore the diagnosis is often difficult and delayed and sometimes is not always possible. This article describes a twelve years old boy with all the clinical signs of immunodeficiency, as confi rmed by laboratory. The main treatment consists of life-long immunoglobulin substitution in intravenous or subcutaneous form.

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Published

15.09.2013

Issue

Section

Case reports

How to Cite

1.
Common variable immunodeficiency – case report. JHSCI [Internet]. 2013 Sep. 15 [cited 2024 Apr. 24];3(2):170-2. Available from: https://www.jhsci.ba/ojs/index.php/jhsci/article/view/119

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