Gastric adenocarcinoma with choriocarcinomatous differentiation in the remnant stomach, 54 years after Billroth II partial gastrectomy

  • Mehmet Yildirim Department of Surgery, Izmir Bozyaka Research and Education Hospital, Izmir, Turkey
  • Nazif Erkan Department of Surgery, Izmir Bozyaka Research and Education Hospital, Izmir, Turkey
  • Enver Vardar Department of Pathology, Izmir Bozyaka Education and Research Hospital, Izmir, Turkey
  • Enver Ilhan Department of Surgery, Izmir Bozyaka Research and Education Hospital, Izmir, Turkey
  • Zehra Erkul Department of Surgery, Izmir Bozyaka Education and Research Hospital, Izmir, Turkey

Abstract

The gastric remnant cancer is defined as a cancer that has developed 5 or more years after distal gastric resection for benign diseases of the stomach. The choriocarcinomatous differentiation of adenocarcinoma in the stomach is a very rare tumor. A 75-year-old woman underwent resection of remnant stomach which she had operated for benign gastric pathology 54 years ago. Pathologic examination of the resection revealed areas of choriocarcinomatous differentiation in addition to classical adenocarcinoma. In the literature on English language, this report presents the first case of adenocarcinoma associated with choriocarcinomatous differentiation in the gastric remnant. The treatment of these patients depends on the clinical setting, and early diagnosis is an important factor for the treatment strategies. Therefore, due to the probability of arising adenocarcinoma in the remnant stomach, the patient should be investigated with endoscopic examination periodically, despite the long postoperative period.

References

1. Costa-Pinho A, Pinto-de-Sousa J, Barbosa J, Costa-Maia J. Gastric stump cancer: more than just another proximal gastric cancer and demanding a more suitable TNM staging system. Biomed Res Int. 2013(2);781896. http://dx.doi.org/10.1155/2013/781896.
2. Sapmaz F, Basyigit S, Uzman M, Simsek G, Akkan T, Nazligul Y. A gastric stump cancer with unusual appearance. Journal of Health Sciences 2015;5(3):104-6.
http://dx.doi.org/10.17532/jhsci.2016.289.
3. Nakao A, Sakagami K, Uda M, Mitsuoka S, Yamashita N, Ito H. Gastric carcinoma with predominant choriocarcinomatous component. Int J Clin Oncol. 1998;3(6):403-5.
http://dx.doi. org/10.1007/BF00539222.
4. Kaminishi M, Shimoyama S, Yamaguchi H, Yamada H, Ogawa T, Oohara T. Classification and carcinogenesis of gastric stump cancer. Gastroenterol Surg.1993;16:1253-65.
5. Lee SM, Kim KM, Ro JY. Variants of gastric carcinoma: Morphologic and theranostic importance. In: Laz«ér D, editor. Gastric carcinoma: New insights into current management. Rijeka, Croatia: In Tech; 2013. p. 195-7. DOI: 10.5772/45896.
6. Ikeguchi M, Kondou A, Shibata S, Yamashiro H, Tsujitani S, Maeta M, et al. Clinicopathologic differences between carcinoma in the gastric remnant stump after distal partial gastrectomy for benign gastroduodenal lesions and primary carcinoma in the upper third of the stomach. Cancer. 1994;73(1):15-21.
http://dx.doi.org/10.1002/1097-0142(19940101)73:1<15::AID-CNCR2820730105>3.0.CO;2-J.
Published
2016-07-03
How to Cite
YILDIRIM, Mehmet et al. Gastric adenocarcinoma with choriocarcinomatous differentiation in the remnant stomach, 54 years after Billroth II partial gastrectomy. Journal of Health Sciences, [S.l.], v. 6, n. 2, p. 133-136, july 2016. ISSN 1986-8049. Available at: <http://www.jhsci.ba/OJS/index.php/jhsci/article/view/352>. Date accessed: 25 sep. 2018. doi: https://doi.org/10.17532/jhsci.2016.352.
Section
Case reports

Keywords

Gastric remnant;Choriocarcinoma